Measurement of total antioxidant response in colorectal cancer using a novel automated method
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چکیده
Colorectal cancer is one of the most common neoplastic diseases in humans. In all, 50% of the Western population develops a colorectal cancer by the age of 70, and in about 1 in 10 of these individuals. There are many factors related to reactive oxygen species (ROS) and free radicals involved in the initiation and progression of cancer (1). The role of oxidative stress in the pathogenesis and development of human colorectal cancer has been suggested in various reports. The gastrointestinal tract is particularly susceptible to attack by reactive oxygen species, which leads to carcinogenesis. Antioxidants play an important role in the defense against reactive oxygen species (2); however, information on biochemical
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تاریخ انتشار 2009